Opportunity Information: Apply for CDC RFA GH19 1962

The grant opportunity "Strengthening Laboratory, Blood Safety, and Infection Prevention and Control Capacities in Liberia" (CDC RFA GH19 1962) is a CDC cooperative agreement designed to help Liberia continue rebuilding and stabilizing key parts of its health system after the 2014-2016 Ebola outbreak revealed major gaps in outbreak preparedness. During that crisis, Liberia faced serious constraints in basic public health defenses: laboratories often could not quickly test for infectious diseases, blood supplies were unreliable and blood services were underdeveloped, and infection prevention and control (IPC) practices in health facilities and laboratories were weak or sometimes absent. While substantial improvements were made after 2014 through investments and partner support, the CDC notes the overall system is still fragile and requires sustained, targeted strengthening to prevent future outbreaks from escalating.

The core purpose of the award is to reduce transmission of epidemic-prone diseases and limit antimicrobial resistance within healthcare settings by strengthening three connected areas: laboratory systems, blood safety and transfusion services, and IPC programs. On the laboratory side, the opportunity focuses on building a more competent laboratory workforce, expanding diagnostic capacity so priority infectious diseases can be confirmed quickly, and reinforcing improvements through laboratory quality management systems. The logic is straightforward: fast, accurate test results are often the turning point in stopping an outbreak early, because they enable timely case confirmation, isolation decisions, contact tracing, and appropriate clinical management. Quality management is emphasized because improved testing is not just about equipment; it also depends on standardized procedures, reliable workflows, supervision, and consistent performance.

For blood safety, the grant supports improvements in transfusion practices and the systems needed to build and maintain quality blood transfusion services. The opportunity highlights that safe and reliable blood transfusion services reduce infection risks and improve patient outcomes, which is especially important in settings where maternal hemorrhage, severe anemia, trauma, and surgical needs create ongoing demand for blood. The approach described includes strengthening the National Blood Safety Program through technical training, on-site mentorship at multiple levels, implementation of blood safety quality standards, and support for essential equipment and supplies. The emphasis on standards and mentoring suggests CDC is aiming for durable operational improvements rather than one-time trainings.

IPC strengthening is presented as equally central, reflecting lessons learned from earlier programming that showed training alone is not enough. The opportunity specifically points to mentorship as a key factor in helping healthcare workers retain knowledge and consistently apply correct IPC practices on the job. Stronger IPC programs are positioned as a frontline defense that protects patients and healthcare workers, reduces healthcare-associated infections, and helps prevent facility-based amplification of outbreaks. The grant ties IPC improvements not only to epidemic control but also to limiting antimicrobial resistance, since better infection control reduces infection spread and can reduce inappropriate antibiotic use driven by preventable transmission.

This funding builds on activities supported under a prior CDC award (CDC-RFA-GH15-1630), and it incorporates findings from that work. Reported progress from the earlier efforts included improved laboratory diagnostics through intensive technical training paired with embedded mentorship, strengthened by quality management activities; improved blood transfusion services through training and on-site mentoring for blood safety program staff, backed by standards, equipment, and supplies; and IPC gains achieved through healthcare worker training that included mentorship to ensure practices actually changed at the facility level. The opportunity also stresses system-level sustainability measures that help improvements last beyond a single project cycle, such as technical assistance to the Government of Liberia to develop supportive national policies and strategic plans, creation of protocols and procedures to institutionalize better practices, and training-of-trainers models to expand and maintain workforce capacity over time.

Administratively, this is a discretionary funding opportunity from the U.S. Department of Health and Human Services, Centers for Disease Control and Prevention (CGH), offered as a cooperative agreement, which typically means the CDC expects substantial involvement and collaboration during implementation. It is listed under CFDA 93.318, with eligibility described as unrestricted (open broadly to entity types, subject to any clarifications in the full notice). The opportunity anticipated a single award, with an award ceiling of $3,500,000. The notice was created May 1, 2019, with an original application deadline of June 3, 2019 (applications due by 11:59 p.m. Eastern Time).

Overall, the grant is aimed at making Liberia better able to prevent, detect, and respond to infectious disease threats by ensuring faster diagnosis, safer blood services, and stronger infection control inside health facilities. It is explicitly aligned with Global Health Security Agenda priorities, reflecting an intent to strengthen core public health capacities that can stop outbreaks near their source before they become national or regional emergencies.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Strengthening Laboratory, Blood Safety, and Infection Prevention and Control Capacities in Liberia" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on May 01, 2019.
  • Applicants must submit their applications by Jun 03, 2019 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $3,500,000.00 in funding.
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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